Endocrinology, Clinical Application and Treatment
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Clinical application of gut microbiota metabolites: A novel opportunity in personalized medicine
Nowadays, metabolomics studies are performed with different approaches to identify biomarkers, clarify the underlying mechanisms of diseases and achieve novel treatment strategies. In this context, gut microbiota-derived metabolites are known as one of the most important mediators of gut microbiota effects on human health and various diseases. Due to the inefficiency of conventional therapies i...
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Diabetic foot ulcer (DFU) is one of the common reasons for non-traumatic amputation of the lower limbs, which requires proper diagnosis, proper collection of specimens, careful selection of antibiotics, treatment of infection based on the disease condition, quick decision about whether or not surgery is necessary and other types of wound care. Probiotics are suggested as non-pathogenic microor...
متن کاملDiagnosis and treatment of diabetic foot infections: adopted IWGDF guidline
Background: Diabetic foot infection is the most common complication of diabetic foot ulcer (DFU) leading to amputation. The treatment requires special attention to disease conditions, proper diagnosis, appropriate sampling for cultures, careful selection of antibiotics, rapid determination of the patient’s need for surgical intervention, and wound care. Clearly a systematic approach or, if poss...
متن کاملAN OVERVIEW OF STEM CELL AND REGENERATIVE MEDICINE RESEARCHES IN IRAN
Background: In many years, finding modern and appropriate treatments for diseases, especially chronic diseases (such as chronic metabolic diseases) have been one of the most important issues. On the other hand, limitations related to organ transplantation have made a serious need for advanced therapeutic strategies. In this respect, researchers have recognized the benefits of stem cells as a su...
متن کاملMetabolomics and Cell Therapy in Diabetes Mellitus
Diabetes with a broad spectrum of complications has become a global epidemic metabolic disorder. Till now, several pharmaceutical and non-pharmaceutical therapeutic approaches were applied for its treatment. Cell-based therapies have become promising methods for diabetes treatment. Better understanding of diabetes pathogenesis and identification of its specific biomarkers along with evaluation ...
متن کاملA survey of clinical practice patterns in diagnosis and management of Cushing\'s disease in Iran
Background: Cushing's disease is the most prevalent cause of endogenous adrenocorticotrophic hormone hypersecretion. The aim of this study was to document the current clinical practice pattern in the management of Cushing's disease by Iranian Endocrinologists to determine their opinions and compare them with the current clinical practice guidelines. Methods: An eight-item questi...
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